Best CBD Oil for Anxiety: The Top Picks for 2021

Coffee Cup CBD Oil Bottle

Anxiety can be disastrous for anyone’s life. Luckily, the best CBD oil for anxiety can be of HUGE help.

When anxiety hits and the feeling of eternal doom comes back to mind, there’s almost no solution (unless you want to numb your brain down with medications).

That’s when cannabidiol enters into play. 

Its almost immediate effects are often looked down upon. But no lie when we say that it calms down even the most anxious people.

Having said that, there’s a lot more to know about CBD and how it helps. Thus, we’re going over EVERYTHING you should understand before picking a CBD oil, plus some EXCELLENT choices we’ve tried and loved.

Check below for more! 

Top 7 CBD Oil Brands for Anxiety of 2021

What We Followed to Recommend These CBD Oil Brands?

To get the best CBD oil for anxiety, we had to go through a set of rules that set the low-quality oils apart from the high-end ones. 

Following is the criteria to follow when choosing CBD oil brands:

Quality Ingredients

Even though CBD oil is not the most complex of supplements you can take, there’s still a lot to disclose. For example, certain ingredients are prohibited, while others need to be at their minimum. Plus, different types of CBD deliver a different result.

Here’s what to know:

Tetrahydrocannabinol (THC)

You’ll want to pick a CBD oil that contains no more than 0.3% THC. This is the component that produces euphoric emotions and sensory impairment. Every one of our products above fits with this description.  Thus, it’s prohibited in the US. 

CBD Isolate 

This is a type of cannabinoid. The “isolate” means it contains no CBG or CBN (other cannabinoids). Thus, it is a purely calming effect, as it has no other compounds that could affect the body’s response. 

Broad-Spectrum CBD 

There’s no THC in this CBD. It may contain other cannabis components, but it’s still the closest you can get to CBD isolate. It may produce slightly stronger results given its additional components. 

Full-Spectrum CBD 

Everything that comes with the cannabis extract will be present in this CBD. This includes CBG, CBN, terpenes, and flavonoids. Plus, it may contain up to 0.3% of THC. 

Terpenes and Flavonoids

These are included with the full-spectrum CBD. Terpenes can promote relaxing effects alongside CBD. Meanwhile, flavonoids are antioxidants that may reduce pain and improve skin issues. 


Also called coconut oil, this allows the CBD to be transported and absorbed by the body. It is the liquid where CBD extracts are poured into. Therefore, a quality MCT oil means a quality CBD oil. Also, it typically has other benefits like improvements in metabolism, weight maintenance, and even enhanced immunity. 

Effects and Strength

We also picked the CBD oils above considering WHAT they were better for (and how much of that was due to their strength).

For example, a mild CBD oil of about 10mg per dose could help relax when sleeping. Meanwhile, a 50mg-per-dose oil could be much more effective at relieving anxiety.

In case of panic attacks, depression, and even inflammation, more potent oils offering 250mg per dose can also help. 

You’ll find CBD oils of all these potencies above. 

Different Flavors 

While not our most important factor to think about, we always prefer brands that offer at least two different flavors.

And in case the oil is thoroughly natural (no artificial taste), we make sure to pick options with nutty tones. They’re often more pleasant than earth-like CBD oils that could be hard to swallow. 

Company Reputation

We also put great attention into the brand’s reputation.

This is difficult to determine how a CBD oil brand is. However, there are hundreds of factors that give us an idea of what we should consider.

First and foremost, we check that there isn’t an FDA warning about the brand. This is the first step into making sure it’s reliable.

Then we consider customer reviews. The product must have at least 50-100 reviews from valid purchases (we check this thoroughly).

And finally, we check ingredients and sources. If a brand can explain with concrete words how their products are made or at least where they come from, they gain reliability points.  

CBD Oil Lifestyle Concept Beauty

Tests and Regulation

Finally, we check whether the brand pays for irregular tests about their products or whether they are tested by independent labs. 

This is a great way to understand what they’re offering and why. We make sure every CBD oil in our listings is independently tested and reviewed to be safe. 

Apart from that, it should comply with most of the country’s regulations. This includes less than 0.3% of THC in the composition. 

Best CBD Oil To Combat Anxiety and Depression in 2021

#1 Fab CBD: Best Overall

When someone looks for the best CBD oil for anxiety, we have no better recommendation than Fab CBD.

It combines the best full-spectrum CBD (traces lower than 0.3% of THC) with MCT oil. 

This combination sets the quality apart from competitors, as it gets double the effectiveness without any of the drawbacks (and quick results). 

Fab CBD offers several strength levels. We tested the 1,200mg and weren’t disappointed.

But more importantly, it features various flavors, like Mint, Berry, Vanilla, Citrus, and the go-to for enthusiasts: Natural. 

We love Fab CBD because it’s one of the few brands with a HUGELY positive reputation. Even better, it has no FDA warnings to worry about (so you’re more than safe with this one). 

CBD Type 

Full-spectrum CBD 


The strongest offers 40mg per dose, considering it comes in a 1,200mg bottle. That’s ideal for taking yourself into an instant nap without thinking about it twice (for several days). 

If you prefer lower dosages for occasional use, the 150mg, 300mg, and 600mg options are also available. 


Almost instant. A single dose can bring your anxiety levels down to its knees. And with the added flavors, it will also delight your tastebuds, so you’ll have nothing to complain about.

We loved it in every sense and would likely keep using (and recommending) this FabCBD oil for a long time. 



Woman CBD Oil Dropper Cup

#2 Medterra CBD: Most Popular

Some brands don’t mind charging you a premium for CBD isolate. 

Medterra does not. 

It is a well-priced CBD oil with the effectiveness necessary to get your anxiety down, relieve some pain, and even help with inflammation. 

Being 99.6% CBD, Medterra claims it’s one of the purest in the market. And that wouldn’t be a lie.

However, what sets this Medterra oil apart is the 500mg bottle that feels like it’s way more than that. It manages to relieve disturbances surprisingly well and without drawbacks.

If you prefer a stronger CBD oil, there’s also a 1,000mg and 3,000mg version. 

The application even comes with serving measurements so you can take exactly what you want. 

And apart from all that, Medterra still puts TONS OF EFFORT in delivering quality products that never disappoint.

This CBD oil is unflavored, so it may have a plain taste. But considering the CBD isolate composition, this is an understandable downside to have. 

CBD Type

CBD Isolate


At 16mg per serving, it is enough to knock you down slowly but surely. Your anxiety will likely go away within minutes.

You can go for the 3,000mg and get 100mg per serving if you prefer a more potent dose. 


No need to wait hours for the CBD to hit. As soon as it starts traveling through the veins within minutes, your brain and body will feel renewed.

Your stress and anxiety will go, so you’ll be ready to stay present again. 



#3 NuLeaf Naturals: Most Potent

Among veterans in the CBD industry, NuLeaf stands up there with the pioneers.

It doesn’t offer the broadest array of products, but its CBD oil will surpass EVERY ONE OF YOUR EXPECTATIONS.

Every dose offers up to 30mg, more than ideal for giving you instant results. The effectiveness is among the best in the market, regardless of the bottle size or strength you pick (300mg, 900mg, 1,800mg, 3,000mg, or 6,000mg)

But it’s not the effectiveness you want to know, but the quality.

NuLeaf takes the extra mile to produce CBD oil using a full-spectrum mix. It is one of the safest considering the ultra-low amounts of THC.

Meanwhile, it is an unflavored oil. You won’t have the vast array of flavors other brands offer, but that doesn’t mean it’s unpleasant. Actually, it has a nutty flavor that many people will appreciate.

CBD Type 



Every bottle, regardless of its strength, offers 30mg per dose. This gets the job done. It is highly effective and will rarely provide side effects. 


The 100% organic production of NuLeaf doesn’t take away any of its effectiveness. 

Thus, you can expect more-than-ideal results in any presentation. It’s perfect for bringing your levels of anxiety down (as well as signs of depression). 



Woman Holding CBD Bottle Manicured Nails

#4 cbdMD: Best Flavor Option

In those cold nights where bones hurt and skin aches, you’ll want a potent CBD oil to relieve your ailments. 

cbdMD can be that option. It becomes the best CBD Oil for arthritis pain by offering between 10mg and 250mg of potency per dose.

But cbdMD is not only about effectiveness. This brand still comes with more-than-ideal prices despite its incredible results.

The flavors go from Orange, Mint, and Berry, to Natural, for those who prefer plain taste for their buds.

If there’s something about this oil you should know is the ISO certification. The lab complies with the highest standards, so you can be sure that it’s thoroughly safe.

And because cbdMD uses a broad-spectrum CBD, you can expect other cannabinoids like CBG and CBN to appear in the formula. This adds up to its relieving effects and performance.

CBD Type

Broad-spectrum CBD


Depending on the bottle you pick, there’s a chance to get ultra-quick effects. For example, only a couple of minutes would be enough if you choose the 7,500mg bottle at 250mg per dose. 

You can also go for the 300mg, 750mg, 1,500mg, 3,000mg, or 5,000mg versions.


Every time we used cbdMD, we obtained almost immediate results. The anxiety-relieving effects matched with the inflammation and bone liberation so we could enjoy deep-sleep nights. 



#5 CBDPure: Best for Purity

Affordability but great effectiveness, CBD Pure does everything.

You get a combination of full-spectrum oil with entirely organic ingredients grown in the US. This ensures thoroughly safe products in any of CBD Pure’s presentations.

But if there’s something about this brand that stands out is the purely CO2-based extraction. This increases the CBD’s purity to keep its efficacy high.

Apart from that, this CBD oil is unflavored, featuring a mild earthy aroma. While not the best for everyone, it adds up to the versatility of the oil (you can use it with any drink).

And because CBD Pure tries its best to provide secure products, its CBD oil is tested by third-party labs. So there’s nothing to worry about. 

CBD Type

Full-spectrum CBD


There are various strength levels to consider, going from 300mg to 600mg and even 1,000mg. In addition, each one offers a different dose level, starting at 10mg, then 20mg, and finally 33mg accordingly.

You’ll get the whole package whether you prefer high strength or mild effects. 


Regardless of what you pick, the oil acts fast and safely. The oil’s purity makes it one of the fastest to deliver calming effects, so there’s no time to waste. We were delighted, especially considering its fantastic cost. 



Woman Adding CBD Oil Tea

#6 CBDistillery: Best for Variety

No other brand offers a broad array of CBD oils like CBDistillery does.

You’ll find full-spectrum, broad-spectrum, and isolates within its catalog. Each bottle offers an impressive result and experience, so people can choose EXACTLY what they want or need.

For example, their THC-Free version contains an isolate that increases strength, offering 33mg of CBD per serving. That may seem like a typical dose, but that’s enough to bring you down instantly, thanks to its highly effective calming effect.

The other versions also stand out, with different levels of potency to enjoy.

CBDistillery also has hemp-certified by US authorities and tested by third parties, so there shouldn’t be any doubt about their safety.

Also, all the CBD oils from this brand are unflavored. So while there’s no taste to enjoy, it adds up to the already versatile offering with different CBD types. 

CBD Type 

Isolate – Full-spectrum – Broad-spectrum CBD 


Its strongest 5,000mg bottle at 30mL can deliver 167mg of CBD per dose. That’s not only ultra-high but sufficient to have an almost instant effect on anyone.

Other varieties go from 500mg, 1,000mg to 2,500mg, delivering between 17mg up to 83mg (so there’s a lot to pick from). 


It doesn’t matter what strength level you pick. The results are the same. CBDistillery is a results-oriented brand that makes it possible for every product to deliver precisely what it’s supposed to. 

We are going back to CBDistillery whenever we want effectiveness and a wide array of options. 



#7 Joy Organics: Best Broad Spectrum 

Even though Joy Organics is one of the youngest brands we found, it’s still one of the best.

Its catalog includes two different types of CBD oils and various flavors to enjoy. This includes full-spectrum and broad-spectrum CBD and flavors like Mint, Orange, Lime, and Lemon.

The exciting part about Joy Organics is how the online marketplace separates its different offerings. As a result, you get the chance to browse through every flavor and potency accordingly, making it easy to decide how much strength and what type of CBD you prefer.

Interestingly, all the reviews and opinions we found about Joy Organics were terrific. This talks positively about its customer service and the quality of the products. 

One important thing to mention is the third-party tests and other laboratory improvements, making Joy Organics one of the safest brands you can go.

CBD Type 

Full-spectrum – Broad-spectrum CBD


The most potent offering from Joy Organics can reach 75mg of CBD per dose. That’s a strong daily dose for most people.

Other strengths go from 15mg up to 45mg per dose, in bottles ranging from 450mg to 1,350mg. 


Considering the flavor options and CBD quantity options, this brand offered not a single drawback regarding results. 

Even the least-potent tinctures were sufficient to work as mild sleeping aids. We can recommend them.



Sad Woman Black Turtleneck Attractive

Facts You Should Know About Anxiety, Depression and CBD Oil

The truth is, anxiety and depression disorders are among the most complex psychological ailments.

But there’s something about their way of working the brain that makes them susceptible to potent supplements like CBD oil.

Let’s give you a more thorough explanation of everything: 

What Causes Anxiety and Depression?

The causes are many. 

For one, these mental disorders may be entirely genetic. Some people have a higher chance of developing the condition if relatives also do.

Then, you will find that medical conditions may also cause anxiety problems. This is generally true with people suffering from neurochemical disorders.

Lack of sleep, low physical activity, and even bad diets may also cause anxiety (and depression). Similarly, traumatic events may cause problems like PTSD that affect the psychology of a person enormously.

Finally, medications may have adverse effects on the mind, triggering unwanted thoughts. 

Can CBD Cure Anxiety and Depression?

Cannabinoids can have exceptional improvements in people’s lives. But it is not a cure for anxiety or depression.

The thing is, CBD oil is probably the best treatment as it has the TINIEST number of side effects.

While other medications cause headaches, appetite disorders, agitation, drowsiness, sexual dysfunction, and even bodyweight gain, CBD does none of that.

According to a study from 2018, CBD reduces stress exponentially. This can be a sure-fire way to prevent most depressive and anxious symptoms.

Other studies show positive correlations between CBD consumption and serotonin production (which reduces the likelihood of depression). 

Lonely Woman Park

Science Behind CBD Oil & Anxiety Relief

Still not convinced that CBD oil can be helpful? Don’t worry, we have PROOF. 

Here are a few questions you may have with their relevant science-based answers: 

Does CBD Help with Anxiety Relief?

One study from 2019 tested the effects of CBD products on 72 subjects. At the end of the study, 79% of the participants experience positive effects (less stress and better sleep).

Another study from 2019 tested the effects of 300mg of CBD in healthy individuals performing public speaking. Unsurprisingly, the 15 subjects who got this dose experienced decreased anxiety while speaking publicly.

Finally, a study in 2020 also showed intermediate but significant positive effects with CBD supplementation on patients with a high risk of psychosis. Their risk of psychosis and levels of social anxiety decreased. 

How Does CBD Battle Anxiety?

The mechanism is not much of a secret.

The anxiolytic effects of CBD come from how it affects the endocannabinoid system. This is a part of the neurological system that consists of pure cannabinoids (produced in the brain).

When humans consume CBD (cannabinoid), this system activates. This affects many different functions of the brain, including cognition, memory, sleep, mood, and even pain.

What does that mean?

When the endocannabinoid system gets affected by neurochemical unbalances or neurotransmitter failure, the mind gets out of control. Here, unwanted thoughts and feelings start to arise. 

By taking CBD oil, cannabidiol enters into play to help release these symptoms by relaxing the cannabinoid system. It gets the neurotransmitters back to balance, reducing the stress and anxiety effects.

Other Benefits You Can Also Get by Consuming CBD Oils

Even though CBD already seems like the best thing to take, there are still many benefits you may not know about.

These include:

Relieves Pain

An experimental placebo-controlled randomized trial from 2019 showed that patients who take CBD experience less pain than those who don’t.

This hints at the effectiveness of CBD as a pain-relieving component. 

May Relieve Cancer Advancement

While not entirely proved, there’s evidence of CBD’s ability to decrease cancer advancement by killing devil cells in people with cervical cancer.  

According to another study, another form of cancer in the brain may also reduce its advancement with CBD, 

Moreover, CBD reduces symptoms like pain, nausea, vomiting, and similar side effects of chemotherapy.

Improves Heart Health

People with diabetic disorders showed positive improvements with CBD intake, according to a study from 2010. People experienced lower blood pressure after taking CBD.

At the same time, its stress-relieving effects may also promote a reduction in hypertension, helping to keep the heart at rest. 

CBD Improves Sleep

By reducing stress and relieving anxiety, the body calms down faster and gets into sleep mode without trouble.

CBD also relieves pain which could help with sleep even more.  

CBD Helps with Agitation

Agitated and irritated individuals can reduce their negative emotions by taking CBD. It’s known that its anxiolytic and serotonin-boosting benefits can reduce people’s agitation.

Moreover, CBD works as a short-term and long-term improvement, working as an excellent treatment for people with chronic agitation. 

Helps with Skin Problems

Because CBD contains tons of antioxidants (flavonoids), it can help as a skin-improving supplement.

Those with skin irritations and rashes may experience no problems after taking CBD.

Also, it may help keep the skin smooth and prevent acne, which is a huge advantage to consider. 

CBD Oil Dosage Guide for Long Term Users

Most CBD oils come in dropper bottles, with measurements for different dosages, depending on personal preferences or needs.

These droppers typically offer 1ml of the oil. However, taking an entire dropper (1 ml) generally is not a good idea.

That’s why they deliver drops (about 0.05 ml). Each drop will add up to the total amount of CBD per bottle (the amount can go from 300mg to 12,000mg).

For example, if a 10mL bottle offers 5,000mg, that would be about 25mg per drop. At the same time, if a 10mL bottle contains 10,000mg, that would mean 50mg per drop. 

Anyone who wants to take CBD for a long time should consider their ideal dosage. Generally, it’s always worth starting with small dosages (lower than 50mg) per day.

So if you have a CBD oil offering 25mg per drop, you should take no more than 2 drops to prevent unwanted effects.

As you get accustomed to the CBD, you may start to add an additional dose to your daily intake.  

Long-term takers can dose up to 1,500mg every day without side effects.

Known Side Effects of CBD Oil

Knowing how much CBD oil you can take won’t be enough. 


Because everyone reacts differently to it.

Here are a few exciting negatives about taking CBD oil to consider:

General Side Effects from CBD

There aren’t many physical or psychological side effects to be scared of when it comes to CBD. But it’s still worth knowing that side effects still occur, especially in those who aren’t accustomed. 

These side effects include:

  • Diarrhea
  • Somnolence
  • Fatigue
  • Nausea
  • Headaches

According to the study from 2018, these effects happened in participants who took more than 1,500mg of CBD per day. 

Hypotension (Low Heart Rate)

There aren’t many studies to say this with enough confidence, but there’s evidence that CBD may cause hypotension.

When blood pressure goes too low, the brain and body start to shut down, causing drowsiness, fuzziness, and dizziness. 

Liver Toxicity

A study on mice showed that CBD could damage the liver over time. This study, however, confirms that mice were administered more-than-ideal doses of CBD. 

That’s why it’s not clear whether it can cause issues, but just like everything, unhealthy amounts could be problematic in the long term. 

CBD and High-Fat Meals

In this case, CBD won’t cause any problems directly. But a study confirms that taking CBD with high-fat meals could cause slightly higher effects from the CBD.

That means the typical CBD experience could be enhanced to the point of causing problems like nausea and diarrhea. This happens because fats from food make it easier for CBD to travel through the blood at higher rates. 

Cropped Woman CBD Oil

CBD And Other Medications 

There isn’t a study that confirms how CBD could be damaging to people who are taking medications. 

Having said that, there’s evidence that CBD inhibits the CYP3A4 enzyme. This enzyme is essential for some medications, as it helps to break them down and absorb them more effectively.

The problem is that people who take CBD and don’t feel the effects of other medications may increase their doses. As a result, they may end up overmedicating themselves. 

Always Talk to Your Doctor FIRST

While most side effects from CBD are mild, it’s still important to always talk to a professional before taking anything.

The reason is that CBD still causes slight but sure effects on the mind, something that could cause in many people’s lives. 

To prevent that, always get confirmation from a professional. This may include supervision and recommendations, including the dosage, schedule, and even the type of CBD you could take.

By the way, in case you’re already taking CBD and don’t feel well, consult a professional before taking any further steps. 

Beginners Guide on How Should You Purchase the Oil Online?

Buying CBD oil online shouldn’t be much of a problem as long as you do it from a reliable source. To know whether it’s reliable, check these tips:

  • It should be the official page from the company
  • It should explain all the benefits as well as the side effects of the product
  • It should include specific amounts of CBD per bottle 
  • It should state the exact amounts of CBD per dose 
  • It should describe all the ingredients and type of CBD in the bottle

If the site you’re buying from is from an official brand and provides all the data above, then you can proceed to make your purchase online with no fear. 

Legal Factors to Consider

It is always important to remember that CBD products are legal on a federal level. That means every state in the US should accept CBD oils as a legitimate source of anxiety relief.

But it’s not always as good as it sounds. 

Some states still consider non-prescribed CBD products to be illegal. And in some cases, even punishable by law to own them.

Apart from that, CBD products should be FDA-approved. This would prevent any unwanted situation in different states in the country. 


So, did you find the best CBD oil for anxiety?

With all the information above, this shouldn’t be much of a problem.

Pick the right one, take it whenever you start to feel anxious, and your anxiety may go away slowly but surely.

Just remember, this is not the only solution for anxiety, but it’s undoubtedly one of the best.

So, what are you waiting for? 

About the Author: I am Marcel Rozario, and I’m a social activist and Part-time blogger. I have been an avid enthusiast of cooking, organic food, and alternative medicine. Nerd of sorts. I have been following my pursuits very closely and like to blog about what I have learned.

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